“Ernst Mayr” pioneered the currently accepted definition of a “Biological Species concept”

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Human genome encodes 19 different Wnt proteins, and essential for critical developmental events, including:

Brain development

Limb patterning

Organogenesis

Formation of osteoblasts

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Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins

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Structure of Wnt proteins 

22 cysteine residues, which form disulfide bridges that maintain a globular secondary structure.

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Wnt = wingless + integrated

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Wnt proteins are modified by linkage of a monounsaturated fatty acid, palmitoleic acid, to a serine in the middle of the protein.

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Lipid modifications of Wnt are catalyzed by the 

O-acetyltransferase Porcupine.