Principles & methods of taxonomy

There are four taxonomic fundamental components which simplify the process of identification up to species level.

I.Characterization

II. Identification

III. Nomenclature

IV. Classification

TLS Online TPP Program

#Id: 10079

#XL - T Zoology

Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton.

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#Id: 10080

#XL - T Zoology

Integrins bind extracellular matrix (ECM) glycoproteins, 

1. Laminins  

2. Collagens 

3. Fibronectin

4. Vitronectin

TLS Online TPP Program

#Id: 10081

#XL - T Zoology

Fibronectin binds to integrin through an RGD motif.

TLS Online TPP Program

#Id: 10082

#XL - T Zoology

The binding of integrins to their ligands depends on extracellular divalent cations(Ca+2 & Mg+2)

TLS Online TPP Program

#Id: 10083

#XL - T Zoology

The α subunit of each integrin is the primary determinant of its extracellular ligand specificity

TLS Online TPP Program

#Id: 10084

#XL - T Zoology

Several integrin α subunits contain, I-domain, which can mediate binding of integrins to various collagens in the ECM.