#Id: 10291
#XL - Q Biochemistry
The second phase of T-cell development
1.Positive selection: Selection for those cells whose T-cell receptors engage self-MHC.
2.Negative selection: Selection against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations.
3.Lineage commitment: Commitment of thymocytes to effector cell lineages, including CD4 helper or CD8 cytotoxic populations
