Amla (gooseberry)

Family:phyllanthaceae

Botanical Name:phyllanthus emblica

Gooseberries are edible and can be eaten raw.

Used to treat:- Diabetes

Pain and swelling of the

pancreas

cancer, Upset stomach

eye problems, joint pain

TLS Online TPP Program

#Id: 9610

#XL - T Zoology

Insulin receptor, form disulfide-linked dimers in the absence of hormone.

TLS Online TPP Program

#Id: 9611

#XL - T Zoology

Binding of ligand to predimerized but inactive RTK alters the conformation of the dimer in such a way that the receptor’s kinase becomes activated.

TLS Online TPP Program

#Id: 9612

#XL - T Zoology

TLS Online TPP Program

#Id: 9613

#XL - T Zoology

In the absence of insulin, the extracellular domain adopts a symmetric inverted U-shaped conformation. 

TLS Online TPP Program

#Id: 9614

#XL - T Zoology

Upon insulin binding, the extracellular domain is converted into a T-shaped conformation that brings the transmembrane domains together.

TLS Online TPP Program

#Id: 9615

#XL - T Zoology

Four related EGF receptors participate in signaling by the many members of EGF family :

In the mouse - Erb-B1, 2, 3, and 4

In humans - HER 1, 2, 3, and 4