Mechanism of action of HIV protease

TLS Online TPP Program

#Id: 9333

#XL - T Zoology

An evolutionarily conserved family of receptor serine kinases - TGF-β receptor family

TLS Online TPP Program

#Id: 9334

#XL - T Zoology

An evolutionarily conserved family of signaling molecules, TGF-β superfamily includes: 

TGF-β family, Nodal and activin families, BMPs, Vg1 family, GDNF, AMH

TLS Online TPP Program

#Id: 9335

#XL - T Zoology

Drosophila homolog of TGF-β = Dpp

TLS Online TPP Program

#Id: 9336

#XL - T Zoology

Kinase domains in TGF-β receptors phosphorylate and trigger the activation of a conserved class of transcription factors - Smads

TLS Online TPP Program

#Id: 9337

#XL - T Zoology

Principal function of all 3 human TGF-β isoforms, TGF-β1, 2, and 3:

Prevent cell proliferation by inducing the synthesis of p15 INK4B

TLS Online TPP Program

#Id: 9338

#XL - T Zoology

Monomeric active forms of all members of the TGF-β family (3 conserved intramolecular disulfide Linkages) contain a conserved cysteine residue that forms a disulfide bond links TGF-β monomers into functional homodimers

and heterodimers