TLS Online TPP Program

#Id: 9046

#XL - T Zoology

Monomeric G proteins, including Ras and various Ras-like proteins, do not directly bind to receptors but act as intermediate proteins in signal transduction pathways.

TLS Online TPP Program

#Id: 9047

#XL - T Zoology

Monomeric G proteins are evolutionarily ancient, as evidenced by their widespread functions examples include: 

eIF2

EF1α and EF2

Ran

Sar

Rab

Rho, Rac, and Cdc42

TLS Online TPP Program

#Id: 9048

#XL - T Zoology

All G protein–coupled receptors contain seven transmembrane α-helical regions (H1–H7). In many GPCRs a short α helix H8 lies parallel to the membrane surface, and a covalently bound palmitic acid group

TLS Online TPP Program

#Id: 9049

#XL - T Zoology

Three principal classes of G PCR that bind their ligand in different ways:

TLS Online TPP Program

#Id: 9050

#XL - T Zoology

Member of family A of GPCRs -β-adrenergic receptors

Member of family B of GPCRs -glucagon receptor 

Member of family C of GPCRs -glutamate receptor

TLS Online TPP Program

#Id: 9051

#XL - T Zoology