The two diastereomers of glucose in its "pyranose" form are called the alpha (a) and beta (B) isomers, which differ in the orientation of the OH at C-1

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Mating pathway in the yeast S. cerevisiae, is a MAP kinase cascade which linked to GPCRs.

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Two mating types of yeast cells are: 

1. a 

2. α

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Haploid yeast cells secrete protein signals known as pheromones, which induce mating between opposite mating types.

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An a haploid cell secretes the a mating factor and has GPCRs for the α factor on its cell surface; an α cell secretes the α factor and has GPCRs for the a factor.

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Activation of the MAP kinase pathway by either the a or the α GPCRs induces transcription of genes that inhibit progression of the cell cycle

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The receptors for yeast α and a mating factors are coupled to the same trimeric G protein.