Membranes of late endosomes and lysosomes contain V-class proton pumps that act in concert with Cl- channels to acidify the vesicle lumen.

TLS Online TPP Program

#Id: 8148

#XL - Q Biochemistry

Depolymerization of the clathrin coat into triskelions  by Cytosolic Hsp70

TLS Online TPP Program

#Id: 9978

#XL - T Zoology

β-catenin binds to TCF to displace the Gro repressor and recruits co-activator proteins Pygo, LGS, to activate target gene expression.

TLS Online TPP Program

#Id: 9562

#XL - T Zoology

Neutral theory of molecular evolution

Developed by Motoo Kimura, who argued that most of the evolution of DNA sequences occurs by chance (genetic drift) rather than by natural selection. 

TLS Online TPP Program

#Id: 9541

#XL - T Zoology

James Hutton and Charles Lyell – Uniformitarianism

Darwin was greatly influenced by Lyell’s teachings, and he adopted uniformitarianism in his thinking about evolution.

TLS Online TPP Program

#Id: 7916

#XL - Q Biochemistry

Energy inputs are needed to Import proteins into mitochondria

Chaperone proteins (Hsp70& Hsp90)

An H+ electrochemical gradient, or proton-motive force