Common mechanisms for enzyme-catalyzed bisubstrate reactions

TLS Online TPP Program

#Id: 9474

#XL - T Zoology

SHP1 

Binding of an SH2 domain to a phosphotyrosine in the activated receptor unmasks its phosphatase catalytic site

TLS Online TPP Program

#Id: 9057

#XL - T Zoology

glutamate (E200) and arginine (R209) participate in binding of cAMP, which causes a conformational change in the loop that prevents binding of the loop to the C subunit.

TLS Online TPP Program

#Id: 9426

#XL - T Zoology

TLS Online TPP Program

#Id: 7897

#XL - Q Biochemistry

Chloramphenicol, blocks protein synthesis by bacterial and mitochondrial ribosomes

Cycloheximide, does not affect protein synthesis by mitochondrial ribosomes

TLS Online TPP Program

#Id: 8947

#XL - T Zoology

An inhibitor of Kin4, called Lte1, localizes to the bud but is absent from the parent cell; it inhibits any residual Kin4 that leaks into the bud.