formin family members have two adjacent domains:

FH1- rich in proline, landing site for profilin–ATP–G-actin

FH2 - form a dimer and nucleate filament assembly

TLS Online TPP Program

#Id: 8599

#XL - R Botany

Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.

TLS Online TPP Program

#Id: 8600

#XL - R Botany

R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

TLS Online TPP Program

#Id: 8601

#XL - R Botany

TLS Online TPP Program

#Id: 8602

#XL - R Botany

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8603

#XL - R Botany

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28 

TLS Online TPP Program

#Id: 8604

#XL - R Botany

G1/S Cyclin–CDKs

In human - cyclin E-CDK 2 

In budding yeast - CIn 1/2-Cdc 28