One NPF is called WASp, as it is defective in patients with Wiskott-Aldrich syndrome.

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#XL - Q Biochemistry

MICOS mediates close juxtaposition of the outer membrane and inner membrane by binding to outer membrane–associated proteins

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#XL - Q Biochemistry

The binding partners for MICOS in the outer membrane are Tom and SAM protein complexes, (involved in import of proteins into the mitochondria). 

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#XL - Q Biochemistry

MICOS function as a diffusion barrier to prevent mixing of the distinct proteins and lipids in the boundary membrane and crista membranes.

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#XL - Q Biochemistry

The most abundant protein in the outer mitochondrial membrane is a mitochondrial β-barrel porin called VDAC (voltage-dependent anion channel).

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#XL - Q Biochemistry

VDAC 

A multifunctional transmembrane channel protein (similar in structure to bacterial porins) allow passing of  ions and most small hydrophilic molecules (up to about 5000 Da).

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#XL - Q Biochemistry

Mitochondria are associated with the cytoskeleton, which determines their distribution in different cell types.