The short (∼20 amino acid) C-terminal tails of both α- and β-tubulin that protrude from the microtubule are enriched in glutamic and aspartic acids, the surface of the microtubule possesses a net negative charge.

TLS Online TPP Program

#Id: 8547

#XL - Q Biochemistry

The irreversible inhibitors cannot be removed by simple physical techniques such as dialysis, is to reduce the amount of enzyme available for reaction.

TLS Online TPP Program

#Id: 9959

#XL - T Zoology

Wnt = wingless + integrated

TLS Online TPP Program

#Id: 8169

#XL - Q Biochemistry

Rab·GTP is enabled to bind to a variety of different proteins, known as Rab effectors.

TLS Online TPP Program

#Id: 9328

#XL - T Zoology

Arrestin binds tightly to rhodopsin only when rhodopsin kinase has phosphorylated a sufficient number of C-terminal serines and threonines.

TLS Online TPP Program

#Id: 8616

#XL - T Zoology

Phosphorylation of T14 and Y15 in this G-loop

introduces negative charge that electrostatically interferes with the binding of ATP in the catalytic pocket.