The short (∼20 amino acid) C-terminal tails of both α- and β-tubulin that protrude from the microtubule are enriched in glutamic and aspartic acids, the surface of the microtubule possesses a net negative charge.

TLS Online TPP Program

#Id: 9992

#XL - T Zoology

Wnt/PCP signaling 

Functions to regulate the actin and microtubule cytoskeleton, & influences cell shape and behaviour (migration).

TLS Online TPP Program

#Id: 9993

#XL - T Zoology

Planar Cell Polarity 

direct cells to divide in the same plane (rather than forming upper and lower tissue compartments) and to move within that same plane

TLS Online TPP Program

#Id: 9994

#XL - T Zoology

The Wnt-Ca2+ pathway is initiated by Frizzled receptors activating a classical G protein-coupled signaling pathway.

TLS Online TPP Program

#Id: 9995

#XL - T Zoology

TLS Online TPP Program

#Id: 9996

#XL - T Zoology

In Wnt-Ca2+ pathway, Wnt binding to the receptor protein possibly Ryk, alone or in concert with Frizzled.

TLS Online TPP Program

#Id: 9997

#XL - T Zoology

Frizzled-G protein signaling activates PLC-beta, which cleaves PIP2 into DAG and IP3.