Uncompetitive inhibitors bind only to the enzyme-substrate complex and not to the free enzyme. 

TLS Online TPP Program

#Id: 9888

#XL - T Zoology

Don’t eat me

Don’t eat me” signal, the protein CD47. CD47, recognized by the SIRP-α receptor on macrophages.

TLS Online TPP Program

#Id: 9889

#XL - T Zoology

Apoptotic cells attract phagocytes by releasing the lipid mediator lysophosphatidic acid, which functions as a chemoattractant

TLS Online TPP Program

#Id: 9890

#XL - T Zoology

Conserved motifs, usually present in many copies on the surface of a bacterium, fungal cell, parasite, or virus particle, are called pathogen-associated molecular patterns (PAMPs).

TLS Online TPP Program

#Id: 9891

#XL - T Zoology

Pattern recognition receptors (PRRs)

Receptors of the innate immune system that recognize molecular patterns or motifs present on pathogens but absent in the host.

TLS Online TPP Program

#Id: 9892

#XL - T Zoology

Pattern recognition

Families of PRRs (TLRs, CLRs, RLRs, and NLRs) recognize a wide variety of PAMP (and DAMP) ligands.

TLS Online TPP Program

#Id: 9893

#XL - T Zoology

Toll-Like Receptors Recognize Many Types of Pathogen Molecules - Vertebrate Toll-like receptors  are dimers of chains with extracellular leucine-rich (LRR) domains that bind PAMPs and DAMPs.