The Hydrophobic Effect Has the Greatest Influence on Protein Stability. The hydrophobic effect, which causes nonpolar substances to minimize their contacts with water, is the major determinant of native protein structure.

TLS Online TPP Program

#Id: 1346

#XL - T Zoology

Post-translational modifications of the CAAX motifs determine the subcellular localization and correct biological function of Ras proteins.

TLS Online TPP Program

#Id: 1347

#XL - T Zoology

SOS – Ras GEF

NF1 - Ras GAP

TLS Online TPP Program

#Id: 1348

#XL - T Zoology

RasD or RasONC  Replacement of the normal glycine 12 with any other amino acid (except proline) “locks” Ras in the active GTP-bound state.

TLS Online TPP Program

#Id: 1349

#XL - T Zoology

RAF (also known as MAPKKK),  A ser/thr protein kinase

TLS Online TPP Program

#Id: 1350

#XL - T Zoology

KSR (Kinase suppressor of Ras) is a pseudogene homolog of RAF Involve in the activation of RAF

TLS Online TPP Program

#Id: 1351

#XL - T Zoology

CNK serves as a molecular scaffold platform for KSR-mediated RAF activation