At the same time, Plk1 phosphorylates the Rho-GAP component, to form an active Centralspindlin-Ect2 complex. 

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Lysine acetylation 

ε-amino group of a specific lysine of α-tubulin

Microtubules are stabilized against breakage (centrioles, basal bodies, & primary cilia)

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Lysine acetylation & Detyrosylation are found only on α-tubulin and are absent from β-tubulin.

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Post-translational modifications of tubulin:

Lysine acetylation

Detyrosylation

Polyglutamylation

Polyglycylation

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#Id: 8518

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Defects in LIS1 

Miller-Dieker lissencephaly

means “smooth brain”