Chk1, Chk2, and MK2

cause cell cycle arrest by inhibiting Cdc25

stabilizing the transcription factor p53, which induces the transcription of CKI p21 

TLS Online TPP Program

#Id: 10100

#XL - T Zoology

Desmosomes

Adhesion type- Cell-cell

Cytoskeletal attachment- Intermediate filaments

TLS Online TPP Program

#Id: 10101

#XL - T Zoology

The key CAMs in desmosomes are the desmosomal cadherins, desmoglein and desmocollin

TLS Online TPP Program

#Id: 10102

#XL - T Zoology

Desmosomes

Function- Strength, durability, signaling

TLS Online TPP Program

#Id: 10103

#XL - T Zoology

Hemidesmosomes

Adhesion type- Cell-matrix

Cytoskeletal attachment- Intermediate filaments

TLS Online TPP Program

#Id: 10104

#XL - T Zoology

The principal ECM adhesion receptor in epithelial hemidesmosomes is integrin α6β4.

TLS Online TPP Program

#Id: 10105

#XL - T Zoology

Hemidesmosomes

Function- Shape, rigidity, signaling