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Like SOCS proteins in the cytokine signaling, 
Smad7 also recruits an E3 ubiquitin ligase that targets TGF-β receptors for degradation.

#XL - T Zoology #TGF-β Signaling #Part B Pointers
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#XL - Q Biochemistry

T-cell lineage

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Anterograde transport
COPII vesicles = ER to Golgi

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#XL - T Zoology

Male stickleback fish develop red colour on their ventral side in the breeding season and maintain territories. 
When a conspecific male intruder enters their territory, resident males perform an aggressive display. 
The ethologist Niko Tinbergen presented models of different shapes to territorial male stickleback fish. He found that models of any shape elicited aggressive displays, provided the ventral part of the models was coloured red.

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#XL - T Zoology

Wnt/calcium pathway leads to the release of calcium stored within cells, and calcium acts as an important secondary messenger to modulate the function of many downstream targets.

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