The SH2 domain binds strongly to short target peptides containing a critical four-residue core sequence:: 

phosphotyrosine–glutamic acid–glutamic acid–isoleucine

TLS Online TPP Program

#Id: 9893

#XL - T Zoology

Toll-Like Receptors Recognize Many Types of Pathogen Molecules - Vertebrate Toll-like receptors  are dimers of chains with extracellular leucine-rich (LRR) domains that bind PAMPs and DAMPs. 

TLS Online TPP Program

#Id: 9894

#XL - T Zoology

TLS Online TPP Program

#Id: 9895

#XL - T Zoology

TLS Online TPP Program

#Id: 9896

#XL - T Zoology

TLS Online TPP Program

#Id: 9897

#XL - T Zoology

C-type lectin receptor (CLR)

CLRs are plasma membrane receptors and generally recognize carbohydrate components of fungi, mycobacteria, viruses, parasites, and some allergens.

TLS Online TPP Program

#Id: 9898

#XL - T Zoology

Retinoic acid-inducible gene-I-like receptors (RLRs) are soluble PRRs that reside in the cytosol of many cell types.