In unstimulated cells, 

concentration of phosphoinositides is low, and PKB is

inactive because its PH domain physically blocks the kinase active site

TLS Online TPP Program

#Id: 10350

#XL - Q Biochemistry

B cells migrate to the lymphoid follicles. They are directed there by chemokine interactions between CXCL13, which is secreted by follicular dendritic cells (FDCs).

TLS Online TPP Program

#Id: 9309

#XL - T Zoology

Autosomal recessive mutations in the RPE65 gene are a frequent cause of blindness in children.

TLS Online TPP Program

#Id: 9669

#XL - T Zoology

PI-3 kinase was first identified in studies of the 

polyoma virus, a DNA virus

TLS Online TPP Program

#Id: 8231

#XL - T Zoology

Endemic species - Species that live in a single, often isolated, location.

Cosmopolitan Species - with very large geographic ranges that can span several continents.

TLS Online TPP Program

#Id: 8603

#XL - T Zoology

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28