Chemical barriers at these surfaces include specialized soluble substances that possess antimicrobial activity as well as acid pH.

TLS Online TPP Program

#Id: 9663

#XL - T Zoology

Kinase activity associated with receptor activation phosphorylates tyrosines on the bound PLCγ, enhancing its hydrolase activity. 

TLS Online TPP Program

#Id: 10018

#XL - T Zoology

The phosphorylated Ci is proteolytically cleaved by the ubiquitin-proteasome pathway, generating an N-terminal fragment Ci75, which functions as a transcriptional repressor of Hh target genes.

TLS Online TPP Program

#Id: 8158

#XL - Q Biochemistry

Soluble ER-resident proteins contain C-terminal KDEL sorting signal that allows them to be retrieved. 

TLS Online TPP Program

#Id: 8162

#XL - Q Biochemistry

For selective export of certain membrane proteins from the ER contain a di-acidic sorting signal (Asp-X-Glu, or DXE), which binds to the Sec24 subunit of the COPII

TLS Online TPP Program

#Id: 8981

#XL - T Zoology

Population genetics, applies the principles of transmission genetics to large groups of individuals.