Pyroptosis A form of regulated programmed cell death associated with inflammation, and often associated with infection with intracellular pathogens. Mediated by inflammasome-activated caspase-1.

TLS Online TPP Program

#Id: 9929

#XL - T Zoology

TLS Online TPP Program

#Id: 9930

#XL - T Zoology

Variation in Influenza Strains

Antigenic variation in HA and NA is generated by

Antigenic drift involves a series of spontaneous point mutations that occur gradually.

Antigenic shift results in the sudden emergence of a new subtype of influenza.

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#Id: 9931

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Original antigenic sin

Tendency to focus an immune attack on those structures that were present during the original.

This means that our immune systems effectively ignore the subtle changes occurring each year in pathogens

TLS Online TPP Program

#Id: 9932

#XL - T Zoology

TLS Online TPP Program

#Id: 9933

#XL - T Zoology

Bacterial Infections

Bacteria enter the body through several natural routes.

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#Id: 9934

#XL - T Zoology

Cell wall endotoxins of some gram-negative bacteria activate macrophages, resulting in release of high levels of IL-1 and TNF-α, which can cause septic shock.