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Inflammatory response
The response includes both localized and systemic effects, consisting of altered patterns of blood flow, an influx of phagocytic and other immune cells, removal of foreign antigens, and healing of the damaged tissue.

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Snail suppresses the expression of E-cadherin is associated with the EMT

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A cadherin-family member CDHR3, highly expressed in epithelial cells in the human airway, as a receptor for RV-C (virulent class C rhinoviruses).

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In cultured cells, C → Y mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C.

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Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. 

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An integrin molecule is composed of two noncovalently associated transmembrane glycoprotein subunits called α and β.

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