Inflammatory response

The response includes both localized and systemic effects, consisting of altered patterns of blood flow, an influx of phagocytic and other immune cells, removal of foreign antigens, and healing of the damaged tissue.

TLS Online TPP Program

#Id: 9702

#XL - T Zoology

Haploid yeast cells secrete protein signals known as pheromones, which induce mating between opposite mating types.

TLS Online TPP Program

#Id: 9703

#XL - T Zoology

An a haploid cell secretes the a mating factor and has GPCRs for the α factor on its cell surface; an α cell secretes the α factor and has GPCRs for the a factor.

TLS Online TPP Program

#Id: 9704

#XL - T Zoology

Activation of the MAP kinase pathway by either the a or the α GPCRs induces transcription of genes that inhibit progression of the cell cycle

TLS Online TPP Program

#Id: 9705

#XL - T Zoology

The receptors for yeast α and a mating factors are coupled to the same trimeric G protein.

TLS Online TPP Program

#Id: 9706

#XL - T Zoology

Ligand binding to either of the two yeast pheromone GPCRs triggers the exchange of GTP for GDP on the Gα subunit and dissociation of Gα∙GTP from the Gβγ complex.

TLS Online TPP Program

#Id: 9707

#XL - T Zoology

Ligand binding and dissociation of the G protein subunits, the membrane-tethered Gβγ subunit binds the Ste5.