Cyclooxygenase-2 (COX-2)

Enzyme responsible for the formation from arachidonic acid of prostaglandins and other pro-inflammatory mediators.

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#Id: 8605

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S phase Cyclin–CDKs

In human - cyclin A-CDK 2 

In budding yeast - CIb 5/6-Cdc 28

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#Id: 8606

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M phase Cyclin–CDKs

In human - cyclin A-CDK 1

cyclin B-CDK 1

In budding yeast - CIb 1/2/3/4-Cdc 28

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#Id: 8607

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Cdk1 

=Cdc2 (vertebrates and fission yeast)

= Cdc28  (budding yeast)

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#Id: 8608

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There are three D cyclins in mammals:

cyclins D1, D2, and D3

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#Id: 8609

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In free CDK2, the A-loop blocks access of protein substrates to the γ phosphate of the bound ATP.

TLS Online TPP Program

#Id: 8610

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