These cells wall off the organism inside a granuloma called a tubercle. The localized concentrations of lysosomal enzymes in these granulomas can cause extensive tissue necrosis.

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#Id: 7884

#XL - Q Biochemistry

The most abundant protein in the outer mitochondrial membrane is a mitochondrial β-barrel porin called VDAC (voltage-dependent anion channel).

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#Id: 7885

#XL - Q Biochemistry

VDAC 

A multifunctional transmembrane channel protein (similar in structure to bacterial porins) allow passing of  ions and most small hydrophilic molecules (up to about 5000 Da).

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#Id: 7886

#XL - Q Biochemistry

Mitochondria are associated with the cytoskeleton, which determines their distribution in different cell types.

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#Id: 7887

#XL - Q Biochemistry

In highly polarized cells, mitochondria can move long distances being propelled along microtubule tracks

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#XL - Q Biochemistry

In other cells, mitochondria remain fixed at points of high energy demand.

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#Id: 7889

#XL - Q Biochemistry

In mitochondria, the metabolism of sugars is complete: allows 15 times more ATP to be made from a sugar than by glycolysis alone.