Resistance to leishmaniasis correlates well with the production of IFN-ϒ and the development of a TH1 response.

Strains of mice that are naturally resistant to Leishmania develop a TH1 response and produce IFN-ϒ upon infection. 

TLS Online TPP Program

#Id: 9497

#XL - R Botany

HC toxin produced by the fungal pathogen Cochliobolus carbonum of maize (Zea mays) inhibits histone deacetylase activity.

TLS Online TPP Program

#Id: 9047

#XL - T Zoology

Monomeric G proteins are evolutionarily ancient, as evidenced by their widespread functions examples include: 

eIF2

EF1α and EF2

Ran

Sar

Rab

Rho, Rac, and Cdc42

TLS Online TPP Program

#Id: 9622

#XL - T Zoology

Monomeric state of the EGF receptor,

activation loop is situated in the active site of the kinase near the interface of the N and C lobes, blocking the site’s activity; in this way the kinase is maintained in the inactive or “off” state

TLS Online TPP Program

#Id: 9869

#XL - R Botany

UVR8 lacks a prosthetic chromophore

TLS Online TPP Program

#Id: 8631

#XL - T Zoology

APC/C core is organized into three modules: 

1. a scaffold module 

2. a catalytic module

3. a substrate recognition module