Wnt proteins are modified by linkage of a monounsaturated fatty acid, palmitoleic acid, to a serine in the middle of the protein.

TLS Online TPP Program

#Id: 9680

#XL - T Zoology

A FOXO3a mutant in which the three serine residues that are targets for PKB are mutated to alanines is constitutively active

TLS Online TPP Program

#Id: 9681

#XL - T Zoology

PI-3 kinase signaling pathway is terminated by

PTEN phosphatase, which hydrolyzes the 3-phosphate

in PI 3-phosphates.

TLS Online TPP Program

#Id: 9682

#XL - T Zoology

PTEN can remove phosphate groups attached to serine,

threonine, and tyrosine residues in proteins, its ability to

remove the 3-phosphate from PI(3,4,5)P3 is its major function in cells.

TLS Online TPP Program

#Id: 9683

#XL - T Zoology

Loss of the PTEN protein contributes to the uncontrolled growth of cells.

TLS Online TPP Program

#Id: 9684

#XL - T Zoology

Insulin receptor leads to the activation of PKB

TLS Online TPP Program

#Id: 9685

#XL - T Zoology

Main action of the PKB signaling pathway

An increase in uptake of glucose from the blood within minutes.