β-catenin Destruction Complex contains:

Tumor suppressor APC

Dvl protein

Constitutively active protein kinases GSK 3β and CK1

TLS Online TPP Program

#Id: 9505

#XL - R Botany

PthXo1, a TAL effector of the rice pathogen Xanthomonas oryzae, activates expression of the rice gene Os8N3, allowing Xanthomonas to colonize rice plants.

TLS Online TPP Program

#Id: 8031

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 9651

#XL - T Zoology

Phosphorylation by MEK at Y-185 and T-183 in activation loop of MAP kinase leads to a marked conformational change & promotes MAP kinase activation and dimerization.

TLS Online TPP Program

#Id: 9660

#XL - T Zoology

Many RTKs and cytokine receptors specifically activate the γ isoform (PLCγ), which contains an SH2 domain.

TLS Online TPP Program

#Id: 9470

#XL - T Zoology

Phosphorylated STAT dissociates spontaneously from the receptor, and two phosphorylated STAT proteins form a homodimer.