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TLS Online TPP Program

#Question id: 3748

How are the BRCA proteins and their genes implicated in breast cancer?

#XL - Q Biochemistry

  1. The BRCA proteins damage DNA by generating double-stranded breaks which can lead to cancer.

  2. Cells become more susceptible to damage if the genes for these proteins are damaged.

  3. BRCA proteins inhibit excision repair mechanisms.

  4. BRCA proteins initiate recombination between non-homologous DNA sequences.

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TLS Online TPP Program

#Question id: 15489

#XL - S Microbiology

Glyphosate resistance,  Aromatic amino acid are all produced by targeting which pathway
TLS Online TPP Program

#Question id: 15519

#XL - S Microbiology

Double-negative selection perform in between cortex to medulla movements in four stages DN1-DN4 based on the presence or absence of other cell surface molecules, In presence of which genotype cell loses the fate of other lymphoid cell?
TLS Online TPP Program

#Question id: 15520

#XL - S Microbiology

Double-negative (DN) thymocytes that have successfully rearranged their TCRβ chains are valuable, and are identified and expanded via a process known as 
TLS Online TPP Program

#Question id: 15521

#XL - S Microbiology

Rearrangement of the β, γ, and δ loci begins during the
TLS Online TPP Program

#Question id: 15524

#XL - S Microbiology

The bulk of DP thymocyte death (~95%) occurs among thymocytes that fail positive selection because 
TLS Online TPP Program

#Question id: 15525

#XL - S Microbiology

In the instructive model, TCR/CD4 and TCR/CD8 coengagement generates unique signals, if a thymocyte randomly generated a TCR with an affinity for MHC Class I. which thymocyte would bind with MHC class I?