Practice Questions

TLS Online TPP Program

#Question id: 4315

A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. When she finds that the introduced strand separates into single-stranded RNAs, what other evidence of this single-stranded RNA piece's activity would she find?

#Molecular Biology

She can measure the degradation rate of the remaining single strand.
The rate of accumulation of the polypeptide encoded by the target mRNA is reduced.
The amount of miRNA is multiplied by its replication.
The cell's translation ability is entirely shut down.

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TLS Online TPP Program

#Question id: 27067

#Biochemistry

Choose the correct statement regarding the stereochemistry of amino acid

1. 16 amino acid except (Thr, Ile, Cys, Gly) L Fischer projection is equal to S and D is equal to R configuration

2. Thr, Ile is special case because of two chiral center exist in L – Ile/Thr – 2S,3R and D-Ile/Thr–2R,3S configuration

3. Cys exiest in L- Cys – R & D- Cys – S configuration

4. Gly is optically inactive

TLS Online TPP Program

#Question id: 27068

#Biochemistry

Isoleucine and Threonine have two chiral carbons so exists in multiple RS configuration, choose the correct option regarding the given fig.

1. a is D-threonine is (2S, 3S) threonine

2. b is L-threonine is (2R,3S) threonine

3. a is L-threonine is (2S, 3R) threonine

4. b is D-threonine is (2R,3S) threonine

TLS Online TPP Program

#Question id: 27069

#Biochemistry

Choose the correct option regarding the stereochemistry of given compound

TLS Online TPP Program

#Question id: 27070

#Biochemistry

Which of the following statements is correct regarding the stereochemistry of Thr, Ile

1. Thr, Ile is special case because of two chiral center exist in L-Ile in 2R,3S and L-Thr in 2R,3S configuration

2. Thr, Ile is special case because of two chiral center exist in D-Ile in 2R,3S and D-Thr in 2R,3S configuration

3. Thr, Ile is special case because of two chiral center exist in L–Ile in 2S,3R and L–Thr in 2S,3R

4. Thr, Ile is special case because of two chiral center exist in D–Ile in 2S,3R and D–Thr in 2S,3R

TLS Online TPP Program

#Question id: 1232

#Biochemistry

Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2

TLS Online TPP Program

#Question id: 88

#Biochemistry

Anomers can be interconverted ________.