TLS Online TPP Program

#Question id: 45


What is the standard free-energy change, ΔG°, under physiological conditions (E. coli grows in the human gut, at 37 °C) for the following reaction? (Keq = 7.8 × 10^2)

Glucose + ATP → glucose 6-phosphate + ADP

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. 17 kJ/mol

  2. 16.7 kJ/mol

  3. −17 kJ/mol

  4. −16.7 kJ/mol

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TLS Online TPP Program

#Question id: 12185

#Unit 2. Cellular Organization

Mitotic CDKs affect nuclear envelope components by specific mechanism. Which of the following statement is not related to this mechanism?

TLS Online TPP Program

#Question id: 12184

#Unit 2. Cellular Organization

Following graph represent Control of S phase onset in S. cerevisiae by regulated proteolysis of the S phase inhibitor Sic1. 
Which of the following is correct according to graph?

TLS Online TPP Program

#Question id: 12183

#Unit 2. Cellular Organization

Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?

TLS Online TPP Program

#Question id: 12182

#Unit 2. Cellular Organization

The cell cycle is controlled by protein kinases that comprise a catalytic subunit and a regulatory subunit. Which of the following statement is correct regarding to these subunits?

TLS Online TPP Program

#Question id: 4718

#Unit 2. Cellular Organization

All the following statements about destruction of cyclins are true, except:

TLS Online TPP Program

#Question id: 2994

#Unit 2. Cellular Organization

If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?