#Question id: 13119
#Unit 2. Cellular Organization
#Question id: 1374
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to gap junctions.
i. Vertebrate gap junctions are composed of connexins, a family of structurally related transmembrane proteins with molecular weights between 26,000 and 60,000.
ii. Each vertebrate hexagonal particle consists of six noncovalently associated connexin molecules. Each individual connexin molecule has two membrane-spanning α helices with a topology similar to that of claudin.
iii. The permeability of gap junctions is regulated by posttranslational modification of connexins (e.g., phosphorylation) and is sensitive to changes in environmental conditions
such as intracellular pH and Ca2+ concentration, membrane potential, and the intercellular potential between adjacent interconnected cells (“voltage gating”).
iv. The assembly of connexins, their trafficking within cells, and the formation of functional gap junctions apparently depend on N-cadherin and its associated adapter proteins as well as desmosomal proteins.
Which of the following statements are correct?
#Question id: 2991
#Unit 2. Cellular Organization
Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?
#Question id: 10449
#Unit 6. System Physiology – Plant
Cryptochromes, which are predominantly localized in the nucleus, phototropin receptors are associated with the
#Question id: 19019
#Unit 9. Diversity of Life Forms