Methods is the Rosetta program, formulated by David Baker. To satisfy the program’s computational needs, a volunteer network of ∼100,000 computers, known as Rosetta@home, provides the 500,000 or so hours of processing time required to generate a structure;

#Question id: 860

#Unit 1. Molecules and their Interaction Relevant to Biology

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.

#Question id: 654

#Unit 1. Molecules and their Interaction Relevant to Biology

Which pair represents different conformations?

#Question id: 655

#Unit 1. Molecules and their Interaction Relevant to Biology

A change from one conformation of a molecule to another involves ________.

#Question id: 656

#Unit 1. Molecules and their Interaction Relevant to Biology

The ________ is the single shape a protein adopts under physiological conditions.

#Question id: 657

#Unit 1. Molecules and their Interaction Relevant to Biology

Structural proteins that typically assemble into large cables or threads to provide mechanical support to cells or organisms are classified as ________ proteins.

#Question id: 658

#Unit 1. Molecules and their Interaction Relevant to Biology

To what level of structure do α-helices belong?