TLS Online TPP Program

#Question id: 1110


If a pharmaceutical company wished to design a drug to maintain low blood sugar levels, one approach might be to design a compound that does which of the following?

#Unit 4. Cell Communication and Cell Signaling
  1. activates epinephrine receptors in liver cells

  2. increases cAMP production in liver cells

  3. blocks G protein activity in liver cells

  4. increases glycogen phosphorylase activity in liver cells

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TLS Online TPP Program

#Question id: 1533

#Unit 4. Cell Communication and Cell Signaling

Why might using retroviral vectors for gene therapy increase the patient's risk of developing cancer?

TLS Online TPP Program

#Question id: 1386

#Unit 4. Cell Communication and Cell Signaling

The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes. One explanation for the effect of overexpression of the cytoplasmic domain of the integrin beta subunit is that this domain normally functions to bind a cytoplasmic factor necessary for integrin function. Which of the following would be the most informative experiment to identify the cytoplasmic factor?

TLS Online TPP Program

#Question id: 3273

#Unit 11. Evolution and Behavior

The number of forward mutations is equal to the number of reverse mutations then

a) Population is in equilibrium for forward and reverse mutation rates

b) The population is being in Hardy–Weinberg equilibrium

c) No further change in allelic frequency

TLS Online TPP Program

#Question id: 708

#Unit 1. Molecules and their Interaction Relevant to Biology

 Rotational symmetry in proteins is false?

TLS Online TPP Program

#Question id: 16107

#Unit 7. System Physiology – Animal

The most important function of sweat is to remove from the body excess