#Question id: 23844
#Unit 2. Cellular Organization
#Question id: 12316
#Unit 10. Ecological Principles
#Question id: 1518
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.
A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.
B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.
C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.
D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.
Which of the following statements are incorrect?
#Question id: 23386
#General Aptitude
#Question id: 11454
#Unit 7. System Physiology – Animal
The structure of the mammalian middle ear is adapted to convert ________.