Practice Questions

TLS Online TPP Program

#Question id: 7768

The insulin signaling pathway inhibits the synthesis of the Foxo transcription factor proteins that would otherwise increase cellular longevity. Downregulation of the insulin signaling pathway has several other functions, choose right one

#Unit 5. Developmental Biology

It appears to influence metabolism, increasing mitochondrial electron transport.
When the DAF-2 receptor is not active, cells increase the production of enzymes that prevent oxidative damage, as well as DNA repair enzymes.
This lack of insulin signaling increases fertility.
Decrease in DNA synthetic enzymes and in enzymes that protect against ROS is due to the Foxo/DAF-16 transcription factor

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TLS Online TPP Program

#Question id: 20277

#Unit 7. System Physiology – Animal

Which is structurally similar to growth hormone?

d. Bromocriptine

Which of the above is/are correct?

TLS Online TPP Program

#Question id: 20278

#Unit 7. System Physiology – Animal

What type of protein is human growth hormone?

TLS Online TPP Program

#Question id: 20279

#Unit 7. System Physiology – Animal

Which one of the following statements is true with regard to Growth Hormone Secretion?

a. Growth hormone is secreted in a pulsatile pattern.

b. Growth hormone secretory rates are constant over a lifetime.

c. After puberty, the rate of growth hormone secretion declines to a stable level.

d. The highest rates of growth hormone secretion occur during puberty, and the lowest rates occur in senescence.

Which of the following is the correct combination of the statements given above?

TLS Online TPP Program

#Question id: 20280

#Unit 7. System Physiology – Animal

What stimulates growth hormone release?

TLS Online TPP Program

#Question id: 20281

#Unit 7. System Physiology – Animal

The overproduction of growth hormone in adults leads to

TLS Online TPP Program

#Question id: 20282

#Unit 7. System Physiology – Animal

Growth hormone secretion is regulated by negative feedback, three feedback loops including both long and short loops are involved,

a. GHRH inhibits its own secretion from the hypothalamus via an ultrashort-loop feedback.

b. Somatomedins, which are by-products of the growth hormone action on target tissues, inhibit secretion of growth hormone by the anterior pituitary.

c. Both growth hormone and somatomedins stimulate the secretion of somatostatin by the hypothalamus.

d. SRIF is also secreted by the hypothalmus and acts on the somatotrophs to stimulate growth hormone secretion.

Which one of the following represents all correct statements?