#Question id: 889
#Unit 1. Molecules and their Interaction Relevant to Biology
The cis and trans GroEL rings undergo conformational changes in a reciprocating fashion, with events in one ring influencing events in the other ring. The entire GroEL/ES chaperonin complex functions as follows;
a) One GroEL ring that has bound 7 ATP also binds an improperly folded substrate protein, which associates with hydrophobic patches that line the inner wall of the GroEL chamber
b) The GroES cap then binds to the GroEL ring like a lid on a pot, inducing a conformational change in the resulting cis ring
c) Within ~10 s the cis ring catalyzes the hydrolysis of its 7 bound ATPs and releases the resulting Pi , which weakens the interactions binding GroES to GroEL
d) A second molecule of improperly folded substrate protein binds to the cis ring, followed by 7 ATP
e) The binding of substrate protein and ATP to the cis ring conformationally induces the trans ring to release its bound GroES, 7 ADP, and the presumably now better-folded substrate protein
Which of the following is incorrect functions of GroEL/ES chaperonin complex?
#Question id: 23661
#Unit 13. Methods in Biology
#Question id: 11074
#Unit 7. System Physiology – Animal
A 30-year-old woman performs a valsalva maneuver about
30 min after eating lunch. Which of the following best describes the changes in
pulmonary and systemic blood volumes that occur in this woman?
#Question id: 26928
#Unit 10. Ecological Principles
Hutchinsonian niche is proposed by G. Evelyn Hutchinson, that basically based on
#Question id: 5693
#Unit 8. Inheritance Biology
Type of nondisjunction leads to regions of tissue with different chromosome constitutions, a condition known as mosaicism is due to