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TLS Online TPP Program

#Question id: 11484

Two students studying physiology taste a known "bitter" substance, and both report sensing bitterness. They then sample another substance. Student A reports sensing both a bitter taste and a salty taste, but student B reports only a salty taste. What is the most logical explanation?

#Unit 7. System Physiology – Animal
  1. Student A had an allergic reaction to the food, causing him to perceive the food as being bitter.
  2. Student A has normal "bitter" taste buds; student B has defective "bitter" taste buds that result in lower sensitivity to bitterness.

  3. Student A has a protein receptor capable of detecting a bitter molecule found in that substance, whereas student B lacks that particular protein receptor.

  4. Student A has normal saliva, whereas student B's saliva is more alkaline than normal.
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TLS Online TPP Program

#Question id: 865

#Unit 1. Molecules and their Interaction Relevant to Biology

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______
TLS Online TPP Program

#Question id: 864

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one is not the appropriate function of Heat Shock Proteins;
TLS Online TPP Program

#Question id: 862

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

lysosomal protein degradation pathwaysFound in
1. Nonselectivea-well-nourished cells

i-containing the pentapeptide

Lys-Phe-Glu-Arg-Gln

2- Selectiveb-starving cells
TLS Online TPP Program

#Question id: 861

#Unit 1. Molecules and their Interaction Relevant to Biology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 860

#Unit 1. Molecules and their Interaction Relevant to Biology

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.
TLS Online TPP Program

#Question id: 654

#Unit 1. Molecules and their Interaction Relevant to Biology

Which pair represents different conformations?