#Question id: 862
#Unit 1. Molecules and their Interaction Relevant to Biology
Match the following
lysosomal protein degradation pathways |
Found in |
|
1. Nonselective |
a-well-nourished cells |
i-containing the pentapeptide Lys-Phe-Glu-Arg-Gln |
2- Selective |
b-starving cells |
#Question id: 2639
#Unit 2. Cellular Organization
A Lac repressor is a tetramer repressed when bound to the inducer. The trp repressor is a ____________________
#Question id: 7154
#Unit 4. Cell Communication and Cell Signaling
Cancer is believed to often arise from stem cells, rather than fully differentiated cells. Which of the following are consistent with this view?
#Question id: 19077
#Unit 6. System Physiology – Plant
#Question id: 2986
#Unit 2. Cellular Organization
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?