Fever is an abnormal elevation of body temperature. Following statements are regarding to the cellular mechanism of fever.

A. Pyrogens produce fever by increasing the hypothalamic set-point temperature.

B. the mechanism of pyrogen action is increased production of interleukin-1 (IL-1) in phagocytic cells.

C. IL-1 then acts on the anterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

D. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

E. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which decrease the set-point temperature.

Which of the following combination is correct?

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#Question id: 12698

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the net potassium reabsorption rate?

TLS Online TPP Program

#Question id: 12697

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the approximate GFR?

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#Question id: 12659

#Unit 7. System Physiology – Animal

 Which of the following would tend to decrease plasma potassium concentration by causing a shift of potassium from the extracellular fluid into the cells?

TLS Online TPP Program

#Question id: 12658

#Unit 7. System Physiology – Animal

In a person on a high (200 mmol/day) potassium diet, which part of the nephron would be expected to secrete the most potassium?

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#Question id: 12561

#Unit 7. System Physiology – Animal

Given the following measurements, calculate the filtration fraction: glomerular capillary hydrostatic pressure = 50 mm Hg; Bowman’s space hydrostatic pressure = 15 mm Hg; colloid osmotic

pressure in the glomerular capillaries = 30 mm Hg; glomerular capillary filtration coefficient (Kf) = 12 ml/min/mm Hg; and renal plasma flow = 400 ml/min.

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#Question id: 12560

#Unit 7. System Physiology – Animal

If GFR suddenly decreases from 150 ml/min to 75 ml/min and tubular fluid reabsorption simultaneously decreases from 149 ml/min to 75 ml/min, which of the following changes will occur (assuming that the changes in GFR and tubular fluid reabsorption are maintained)?