TLS Online TPP Program

#Question id: 23452


If in the examination hall, you find that the question paper is too tough to be answered satisfactorily by you, the best thing to do for you is to:

#General Aptitude
  1. tell the examiner that the questions are out of course.
  2. provoke the candidates to walk out of the examination hall.
  3. try to know something from your neighbour.
  4. try to solve the questions as much as you know with a cool head.
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TLS Online TPP Program

#Question id: 14764

#Unit 2. Cellular Organization

Match the following proteins (Column I) with their function (Column II). Which of the following is correct?

Column I

Column II

a. Profilin

i. binds to the (+) end of an actin filament, thereby inhibiting subunit addition or loss.

 

b. Cofilin

ii. blocks (−) ends, inhibits filament disassembly, to stabilize filaments

c. Thymosin-β4

iii. involved in actin treadmilling, but it binds specifically to F-actin in which the subunits contain ADP

d. Cap Z

iv. binds ADP–G-actin and catalyzes the exchange of ADP for ATP

e. Tropomodulin

v. binds to ATP–G-actin in such a way that it inhibits addition of the actin subunit to either end of the filament.

TLS Online TPP Program

#Question id: 14763

#Unit 2. Cellular Organization

Which of the following graph shows G-actin polymerize into F-actin.
 

TLS Online TPP Program

#Question id: 14762

#Unit 2. Cellular Organization

Following statements are regarding to determination of filament formation by actin concentration.
A. The critical concentration (Cc) is the concentration at which G-actin monomers are in equilibrium with actin filaments.
B. At monomer concentrations below the Cc, no polymerization takes place. 
C. When polymerization is induced at monomer concentrations above the Cc, filaments assemble until steady state is reached and the monomer concentration falls to Cc.
D. At steady state, the concentration of monomeric actin below the critical concentration.
Which of the following statements promotes spontaneous filament assembly?

TLS Online TPP Program

#Question id: 14761

#Unit 2. Cellular Organization

Following graph represent phases of in vitro G-actin polymerization.



Which of the following is correct?

TLS Online TPP Program

#Question id: 14760

#Unit 2. Cellular Organization

During the microfilament formation, the nucleation phase is marked by:

TLS Online TPP Program

#Question id: 13158

#Unit 2. Cellular Organization

In which process, protein are first encapsulated in a membrane, then the contents of the resulting vesicle are degraded after the vesicle docks with a cytosolic lysosome.