#Question id: 1521
#Unit 4. Cell Communication and Cell Signaling
we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-
A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor
B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-
i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase
ii. to constitutive activation of the kinase activity of the resulting oncoprotein
iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity
which of the following results are displayed after these mutations?
#Question id: 19358
#Unit 13. Methods in Biology
#Question id: 16771
#Unit 13. Methods in Biology
What is the median?
#Question id: 13211
#Unit 6. System Physiology – Plant
#Question id: 3545
#Unit 8. Inheritance Biology
Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. Male with PKU marry with normal female whose father is PKU. What is probability of child affected with PKU?