#Question id: 15306
#Unit 4. Cell Communication and Cell Signaling
The transformation of a normal cell to a cancer cell is accompanied by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;
|
Gene |
Primary tumor |
Proposed function |
|
i) APC |
Colorectal |
Binds β
‐catenin acting as transcription factor |
|
ii) BRCA1 |
Breast |
DNA repair |
|
iii) MSH2, MLH1 |
Melanoma, pancreatic |
p16: Cdk inhibitor ARF: stabilizes p53 |
|
iv) E‐Cadherin |
Breast, colon |
Cell adhesion molecule |
|
v) INK4a |
Colorectal |
Mismatch repair |
|
vi) NF1 |
Neurofibromas |
Activates GTPase of Ras |
Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions; |
#Question id: 4945
#Unit 11. Evolution and Behavior
Which is a defining characteristic that all protobionts had in common?
#Question id: 3490
#Unit 11. Evolution and Behavior
Given below are some behaviors strategies.
A) Fixed action pattern, complex sequence of behavior, Once released and continuous to completion, even when there is change in surrounding environment
B) natural selection select that territorial behavior that is benefit is greater than cost
C) Imprinting, a form of learning in which a very young animal fixes its attention on the first object with which it has visual, auditory, or tactile experience
D) Donor benefits at a cost to the recipient, the behavior is altruistic; when the recipient benefits at a cost to the donor, the behavior is selfish.
Which one of the following correct combination of true and false?
#Question id: 5202
#Unit 11. Evolution and Behavior
Which of the following most correctly describes a shotgun technique for sequencing a genome?
#Question id: 5661
#Unit 5. Developmental Biology
Following statements regarding to the embryogenesis in A. thaliana.
A. The first zygotic division is unequal, with the basal cell larger than the apical cell. The basal cell divides to give rise to the suspensor. The apical cell divides vertically to form a two-celled proembryo, which will give rise to the rest of the embryo.
B. The top most suspensor cell is recruited into the embryo, where it is known as the hypophysis, and contributes to the embryonic root meristem and root cap.
C. The next two divisions produce an eight-cell octant-stage embryo, which develops into a heart-stage embryo of around 32 cells
D. The embryo elongates and the cotyledons start to develop as wing-like structures at one end, while an embryonic root forms at the other. This stage is known as the globular stage.
Which of the following statements are correct?