Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.

A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.

B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.

C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.

D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.

E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.

F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.

Which of the following combination is correct?

#Question id: 10960

#Unit 7. System Physiology – Animal

Why do some malnourished patients bleed excessively when injured?

#Question id: 10961

#Unit 7. System Physiology – Animal

Over the past 12 weeks, a 75-year-old man with a moderate aortic stenosis has developed shortness of breath and chest pains during exertion. He appears pale. Test of his stool for blood is positive. Laboratory studies show the following: hemoglobin 7.2 g/dL, and mean corpuscular volume 75. A blood smear shows microcytic, hypochromic erythrocytes. Which of the following is the most likely diagnosis?

#Question id: 10962

#Unit 7. System Physiology – Animal

A 24-year-old man came into the ER with a broken leg. A blood test was ordered and his WBC count was 22 × 10^3/μl. Five hours later, a second blood test resulted in values of 7 × 10^3/μl. What is the cause of the increased WBC count with the first test?

#Question id: 10963

#Unit 7. System Physiology – Animal

During an inflammatory response, which is the correct order for cellular events?

#Question id: 10964

#Unit 7. System Physiology – Animal

A patient visits his dentist, who notices a sore on the patient’s lip. The sore was unusual in that there was no pain or drainage from the sore. The patient was subsequently admitted to the hospital with a violent shaking chill. His lab values were Hct 30%, platelets 400,000/μl, WBC 4200/μl, 68% lymphocytes, and 20% neutrophils. What is the diagnosis of this patient?

#Question id: 10965

#Unit 7. System Physiology – Animal

Which of the following is a TRUE statement?