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TLS Online TPP Program

#Question id: 720

How would a homopolymer of alanine be more likely to form an alpha helix in water or in a hydrophobic medium?

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. In an aqueous environment, the formation of intrachain hydrogen bonds stabilizes the amide hydrogen atoms and carbonyl oxygen atoms of the polypeptide chain, and so an alpha helix forms. In an hydrophobic environment, these groups are stabilized by interaction with water, and so there is no energetic reason to form an a helix. Thus, the alpha helix would be more likely to form in a aqueous environment.

  2. In a hydrophobic environment, the formation of intrachain hydrogen bonds stabilizes the amide hydrogen atoms and carbonyl oxygen atoms of the polypeptide chain, and so an alpha helix forms. In an aqueous environment, these groups are stabilized by interaction with water, and so there is no energetic reason to form an alpha helix. Thus, the alpha helix would be more likely to form in a hydrophobic environment.

  3. In both hydrophobic environment as well as aqueous environment, the formation of intrachain hydrogen bonds stabilizes the amide hydrogen atoms and carbonyl oxygen atoms of the polypeptide chain, and so an alpha helix forms.

  4. In a aqueous environment, the formation of interchain hydrogen bonds stabilizes the amide hydrogen atoms and carbonyl oxygen atoms of the polypeptide chain, and so an alpha helix forms. In an hydrophobic environment, these groups are stabilized by interaction with water, and so there is no energetic reason to form an alpha helix. Thus, the alpha helix would be more likely to form in a aqueous environment.

More Questions
TLS Online TPP Program

#Question id: 26452

#Unit 3. Fundamental Processes

Holoenzyme shows highest affinity at
TLS Online TPP Program

#Question id: 26451

#Unit 3. Fundamental Processes

Which of the following characteristics of sigma affect non specific binding of the core
TLS Online TPP Program

#Question id: 26450

#Unit 3. Fundamental Processes

Which of the following statements is true regarding bacterial RNA polymerase   
a. Core enzyme can efficiently transcribe both intact and nicked DNA 
b. Sigma destabilizes nonspecifically bound core 
c. Holoenzyme bind tightly to DNA 
d. Higher disassociation rate at lower temperature 
e. Most of the cellular sigma are house keeping gene
TLS Online TPP Program

#Question id: 26449

#Unit 3. Fundamental Processes

Ability of core and holoenzyme to transcribe DNAs differs, so choose which of the following is correct
a.With  subunit, the holoenzyme worked equally well on both intact as well as nicked types of DNA
b.With  subunit, the holoenzyme worked unequally on both intact as well as nicked types of DNA
c.Core subunit α2ββσ can not perform polymerization on to the intact DNA while perform some of the activity on to the nicked DNA
d.Core subunit α2ββσ can not perform polymerization on to the intact DNA AS WELL AS  to the nicked DNA
TLS Online TPP Program

#Question id: 26448

#Unit 3. Fundamental Processes

Choose the correct statement regarding DNA photolyase 
a.MTHF polyglu absorb blue light photon of 300-500 nm
b.And the MTHF polyglu radicalize FADH cofactor
c.And this FADH cofactor donate single electron to CBD 
d.And this FADH cofactor donate many electron to CBD
TLS Online TPP Program

#Question id: 26447

#Unit 3. Fundamental Processes

Which polymerases are template-dependent, they incorporate nucleotides in a manner that is independent of base pairing