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TLS Online TPP Program

#Question id: 767

With respect to how miRNAs work, which, if any, of the following statements, is false?

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. An miRNA is initially composed of two RNA strands, a passenger strand that will be destroyed and a complementary RNA, the guide strand, that is required for it to work.

  2. an active miRNA regulates target protein-coding genes by binding to complementary sequences in the mRNA

  3. A single miRNA normally binds to transcripts from just one target gene

  4. A single type of mRNA can be regulated by multiple different miRNAs.

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TLS Online TPP Program

#Question id: 1534

#Unit 4. Cell Communication and Cell Signaling

Cadherin proteins help animal cells stick (adhere) to each other. Choose which statement about cadherin in cancer cells that are metastasizing (spreading) throughout a patient's body is most likely correct.
TLS Online TPP Program

#Question id: 1533

#Unit 4. Cell Communication and Cell Signaling

Why might using retroviral vectors for gene therapy increase the patient's risk of developing cancer?
TLS Online TPP Program

#Question id: 1532

#Unit 4. Cell Communication and Cell Signaling

For a particular microarray assay (DNA chip), cDNA has been made from the mRNAs of a dozen patients' breast tumor biopsies. Which of the following types of evidence will researchers be looking for in order to determine if the cells are cancerous?
TLS Online TPP Program

#Question id: 1530

#Unit 4. Cell Communication and Cell Signaling

What are the differences and similarities between the transforming genes of retroviruses and those of DNA tumor viruses?
TLS Online TPP Program

#Question id: 1529

#Unit 4. Cell Communication and Cell Signaling

Which of the following statements are true regarding to gain-of-function and loss-of-function mutations with respect to cancer.
TLS Online TPP Program

#Question id: 1528

#Unit 4. Cell Communication and Cell Signaling

Mutation of p53 is described as a dominant-negative mutation. Which of the following statement is correct regarding to the mechanism by which this mutation causes the dominant-negative phenotype?