TLS Online TPP Program

#Question id: 910


Experiments on denaturation and renaturation after the reduction and reoxidation of the —S—S— bonds in the enzyme ribonuclease (RNase) have shown that:

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. folding of denatured RNase into the native, active conformation, requires the input of energy in the form of heat.

  2. native ribonuclease does not have a unique secondary and tertiary structure.

  3. the completely unfolded enzyme, with all —S—S— bonds broken, is still enzymatically active.

  4. the primary sequence of RNase is sufficient to determine its specific secondary and tertiary structure.

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TLS Online TPP Program

#Question id: 742

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

ConformationPhiPsiOmega
A. Alpha helixI. -57P. -47X. 180
B. B sheetII. -135Q. +135Y. 0
C. Polyproline IIII. -83R. +158
D. Polyproline IIIV. -78S. +149

TLS Online TPP Program

#Question id: 741

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of following statements are INCORRECT about secondary structure of proteins

A. Long block of Glu residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation below its pKR value

B. Long block of Lys residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation above its pKR value

C. Long block of Ala residues segment of the chain will not form an alpha helix at pH 7.0 but it ll take helical confirmation below its pKR value

D. Histidine side chain remain uncharged over pH range 3-6

TLS Online TPP Program

#Question id: 740

#Unit 1. Molecules and their Interaction Relevant to Biology

The conformation of the backbone of a polypeptide is described completely by the angle(s) of rotation about which bond(s)?

TLS Online TPP Program

#Question id: 739

#Unit 1. Molecules and their Interaction Relevant to Biology

What is true about the rotation about bonds in a protein backbone?

TLS Online TPP Program

#Question id: 738

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct for peptide bonds

A) C and N are shorter than typical C-N bonds.

B) C and N are longer than typical C-N bonds.

C) C and O are longer than typical C=O bonds.

D) C and O are shorter than typical C=O bonds.

TLS Online TPP Program

#Question id: 737

#Unit 1. Molecules and their Interaction Relevant to Biology

Which structure below indicates the proper hydrogen-bonding pattern between amino acids in an α-helix? (Dashed lines represent the hydrogen bonds.)