TLS Online TPP Program

#Question id: 899


Which statement is true about disulfide bonds and protein folding?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Disulfide bonds have no influence on protein folding since they only form after the protein adopts its native conformation.

  2. Proteins occasionally adopt nonnative conformations and form improper disulfide bonds that can be reversed by the enzyme protein disulfide isomerase.

  3. The folding of the native conformation is influenced more strongly by the formation of disulfide bonds than by the primary structure of a protein.

  4. If a protein forms an improper disulfide bond it is irreversibly inactivated and must be

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TLS Online TPP Program

#Question id: 1235

#Unit 4. Cell Communication and Cell Signaling

Arrange the following events in the proper order in which they occur during transduction of the EGF signal:

a. transphosphorylation of the EGF receptor

b. dissociation of GDP from Ras                   

c. dissociation of Ras from Sos         

d. binding of GRB2 to the EGF receptor      

e. binding of GTP to Ras  

TLS Online TPP Program

#Question id: 1234

#Unit 4. Cell Communication and Cell Signaling

Which of the following mutations would likely have a similar cancer-promoting effect as the RasD mutation?

a. mutation in Grb2 so that it cannot bind Sos

b. mutation in Sos so that it binds Ras independent of Grb2

c. mutation in GAP so that it cannot bind Ras

d. mutation in EGF receptor so that it binds GRB2 independent of EGF

TLS Online TPP Program

#Question id: 1233

#Unit 4. Cell Communication and Cell Signaling

Transphosphorylation (cross-phosphorylation) of receptor tyrosine kinases

a. inhibits catalytic activity.

b. promotes transphosphorylation of additional tyrosine residues.

c. triggers release of the ligand.

d. generates binding sites for signaling molecules.

TLS Online TPP Program

#Question id: 1016

#Unit 4. Cell Communication and Cell Signaling

Lyme disease is an example of a disease

TLS Online TPP Program

#Question id: 1017

#Unit 4. Cell Communication and Cell Signaling

The outbreak of measles within the last few years was due to

TLS Online TPP Program

#Question id: 1018

#Unit 4. Cell Communication and Cell Signaling

Diseases such as ulcers and cardiovascular disease