When stress conditions arise, or when protein synthesis threatens to overwhelm the protein-folding capacity of the ER, unfolded proteins can accumulate. These conditions trigger the unfolded protein response (UPR)

a) unfolded protein response ensures to reduces the rate of protein synthesis by mTOR pathway

b) Amyloid aggregates that form before the UPR can come into play may be removed. Some are degraded by autophagy

c) Amyloid aggregates that can be removed by other mechanism such as lysosomal degradations

d)  UPR also bring the various systems into alignment by increasing the concentration of chaperones in the oxygen deprived conditions

Which of the following statements would be incorrect?

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#Question id: 17267

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. Estimate q, the frequency of allele a, in Generation 1. Show your calculations. 

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#Question id: 15659

#Unit 8. Inheritance Biology

You calculate map distances between genes A, B, and C based on all pairwise dihybrid crosses. When you perform the trihybrid cross to verify your results, you discover that, despite analysis of a very large number of progeny, you have only about half as many double crossover progeny as you expect. Which explanation is the most reasonable?

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#Question id: 15002

#Unit 8. Inheritance Biology

If you performed a dihybrid cross and found that your results were significantly different from the 9:3:3:1 ratio, what would you suspect?

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#Question id: 15001

#Unit 8. Inheritance Biology

You cross true breeding lizards that are either green or albino and discover that all the offspring are striped green and white. Which is the most likely result if you cross two striped lizards?

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#Question id: 15000

#Unit 8. Inheritance Biology

I do a chi square analysis of the offspring from my cross of a black mouse and albino mouse. If the black mouse was heterozygous I should have expected a 1:1 ratio, and I got 6 albino and 2 black mice. What is my chi square value?

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#Question id: 14999

#Unit 8. Inheritance Biology

I know that black coat color in mice is dominant to albino. Black mice get a higher price at the pet store so I am disappointed when I cross a black mouse with an albino mouse and get 6 albino and 2 black mice in the litter. I expected all black. What mistake did I make?