TLS Online TPP Program

#Question id: 889


The cis and trans GroEL rings undergo conformational changes in a reciprocating fashion, with events in one ring influencing events in the other ring. The entire GroEL/ES chaperonin complex functions as follows;

a) One GroEL ring that has bound 7 ATP also binds an improperly folded substrate protein, which associates with hydrophobic patches that line the inner wall of the GroEL chamber

b) The GroES cap then binds to the GroEL ring like a lid on a pot, inducing a conformational change in the resulting cis ring

c) Within ~10 s the cis ring catalyzes the hydrolysis of its 7 bound ATPs and releases the resulting Pi , which weakens the interactions binding GroES to GroEL

d) A second molecule of improperly folded substrate protein binds to the cis ring, followed by 7 ATP

e) The binding of substrate protein and ATP to the cis ring conformationally induces the trans ring to release its bound GroES, 7 ADP, and the presumably now better-folded substrate protein

Which of the following is incorrect functions of GroEL/ES chaperonin complex?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. B and C        

  2. A, C and E

  3. D and E    

  4. ONLY D

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TLS Online TPP Program

#Question id: 10278

#Unit 6. System Physiology – Plant

The type of ATP synthesis, traditionally referred to as substrate-level phosphorylation involves the direct transfer of a phosphate group, which reactions perform substrate-level phosphorylation?

a) Conversion of Glyceraldehyde 3-phosphate to 1,3-Bisphosphoglycerate

b) Conversion of Phosphoenol pyruvate to pyruvate

c) Conversion of Fructose 6-phosphate to Fructose 1,6-bisphosphate

d) Conversion of 1,3-Bisphosphoglycerate to 3-Phosphoglycerate

Find the correct one.

TLS Online TPP Program

#Question id: 10277

#Unit 6. System Physiology – Plant

Each of the nine glycolytic intermediates between glucose and pyruvate is phosphorylated. The phosphoryl groups seem to have many functions such as,

a) The plasma membrane generally lacks transporters for phosphorylated sugars, the phosphorylated glycolytic intermediates cannot leave the cell

b) After the initial phosphorylation, further energy is necessary to retain phosphorylated intermediates in the cell, despite the large difference in their intracellular and extracellular concentrations

c) Phosphoryl groups are essential components in the enzymatic conservation of metabolic energy, Energy released in the breakage of phosphoanhydride bonds is partially conserved in the formation of phosphate esters such as glucose 6-phosphate

d) Binding energy resulting from the binding of phosphate groups to the active sites of enzymes lowers the activation energy and increases the specificity of the enzymatic reactions

which of the following functions shows Importance of Phosphorylated Intermediates?

TLS Online TPP Program

#Question id: 10275

#Unit 6. System Physiology – Plant

In the initial phase of glycolysis, each hexose unit is phosphorylated twice and then split, producing two molecules of triose phosphate, in these reactions included irreversible reaction. How much irreversible reaction is performed in the glycolytic pathway through in this series of reactions?

TLS Online TPP Program

#Question id: 10255

#Unit 6. System Physiology – Plant

In sucrose synthase combines sucrose with UDP to produce fructose and UDP-glucose in the cytosol. What is the function of UDP-glucose pyrophosphorylase?

TLS Online TPP Program

#Question id: 10254

#Unit 6. System Physiology – Plant

Sucrose is split into its two monosaccharide units—glucose and fructose—which can readily enter the glycolytic pathway. Two pathways for the splitting of sucrose are known in plants, both of which take part in the use of sucrose from phloem unloading; Invertase pathway and sucrose synthase pathway, some statements are given about these pathways, which of the following is incorrect?

TLS Online TPP Program

#Question id: 10253

#Unit 6. System Physiology – Plant

Two pathways for the splitting of sucrose are known in plants, both of which take part in the use of sucrose from phloem unloading;