Match the following proteins (Column I) with their function (Column II). Which of the following is correct?

Column I	Column II
a. Profilin	i. binds to the (+) end of an actin filament, thereby inhibiting subunit addition or loss.
b. Cofilin	ii. blocks (−) ends, inhibits filament disassembly, to stabilize filaments
c. Thymosin-β4	iii. involved in actin treadmilling, but it binds specifically to F-actin in which the subunits contain ADP
d. Cap Z	iv. binds ADP–G-actin and catalyzes the exchange of ADP for ATP
e. Tropomodulin	v. binds to ATP–G-actin in such a way that it inhibits addition of the actin subunit to either end of the filament.

#Question id: 10969

#Unit 7. System Physiology – Animal

Which of the following will result in a transfusion reaction? Assume that the patient has never had a transfusion.

#Question id: 10970

#Unit 7. System Physiology – Animal

A mother of blood type A+ who has always been perfectly healthy just delivered her second child. The father is of blood group O−. Knowing that the child is of blood group O− (O, Rh−), what would you expect to find in this child?

#Question id: 10971

#Unit 7. System Physiology – Animal

A pregnant woman comes in for a visit. She is AB Rh− and her husband is A Rh+. This is her first child. What should be done at this time?

#Question id: 10972

#Unit 7. System Physiology – Animal

What is the proper pathway for the extrinsic clotting pathway?

#Question id: 10973

#Unit 7. System Physiology – Animal

An 11-year-old premenstrual female presents with a painful knee after mild trauma. Upon further evaluation you observe soft tissue bruises. The child is an orphan and there is no family history. The foster mother reports no other problems. The aPTT is prolonged and the PT is normal. A complete hematologic workup would yield

#Question id: 10975

#Unit 7. System Physiology – Animal

A teenaged boy with numerous nosebleeds was referred to a physician for evaluation prior to a minor surgery. His prothrombin time (PT) was 11 sec (11–15 sec normal), partial thromboplastin time (PTT) was 58 sec (25–40 sec normal), and bleeding time was 6.5 min (2–7 min normal). Which of the following is most likely abnormal in this young man?